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anti-phospho-ERK (Thr 202 /Tyr 204 ), anti-ERK, anti-tuberous sclerosis complex 1 (TSC1), anti-TSC2 and anti-proliferating cell nuclear antigen (PCNA) were from Cell Signaling (Danvers, MA, USA)
Noom explains that this is because some preparations typically require ingredients that can lower the color category, such as sugar, more salt, cream, or oil
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this, in turn, resulted in the upregulated expression of telomere repeat-binding factor 1/2 (TRF1/TRF2) proteins and strict dependence on p53/p21 signaling, followed by irreversible G2/M cell cycle arrest, ultimately leading to apoptosis
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